Moreover, the Ex4a(+)WT1 isoform and full WT1 isoforms which includes each Ex4a(+) and important WT1 isoforms had been quantified by quantitative real-time PCR (Fig 6C). The outcome confirmed that Ex4a(+)WT1 isoform was increased and important WT1 isoforms ended up decreased by apoptosis. When etoposide was utilised being an apoptosis inducer, the similar effects were attained (details not proven)


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